The Eye in Graves' Disease.

نویسنده

  • I C GILLILAND
چکیده

Classification "Lid lag" True lid lag is virtually specific for hyperthyroidism. It is probably due to increased tone in the levator palpebrae superioris and gives rise to the "staring" appearance. It can be elicited by making the subject follow movements of the finger rapidly up and down. The upper lid can Ibe observed to lag behind the movement of the eyeballs, especially in a downward direction, with the result that a line of sclera can be observed between the lid and the upper margin of the iris during this move'ment. It is commonly bilateral but may be much more marked in the one eye than the other. When this sign is more marked the upper lid may be permanently retracted so that even at rest a margin of sclera may be observed between the upper lid and the upper margin of the iris. This can be conveniently measured, especially in consecutive photographs. These signs usually disappear when the patient becomes euthyroid. The subsequent improvement in the appearance of the patient may give rise to the false impression that the other signs are progressing favourably (Dobyns, 1950).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Prevalence and severity of ocular involvement in Graves’ disease according to sex and age: A clinical study from Babol, Iran

Background: Thyroid-associated eye disease (TED), previously known as Graves’ ophthalmopathy is a cosmetically and functionally debilitating disease that is seen worldwide. The aim of this study was to evaluate the prevalence and clinical severity of ocular manifestations of Graves’ disease according to sex, age and duration in northern Iran. Methods: Between April 2011 and March 2...

متن کامل

Cut off value of technetium uptake in the differential diagnosis of Graves, disease and subacute thyroiditis

Objective(s):The aim of this study was to determine whether technetium (99mTc) uptake is a relevant method for the differential diagnosis of Graves disease and subacute thyroiditis and calculate its cutoff value in case of its relevancy. Methods: A total of 69 patients, who were followed up (>3 months) in our hospital for thyrotoxi...

متن کامل

AUTOANTIBODIES AGAINST THYR OID CONSTITUENTS AND CIC IN GRAVES\' DISEASE ASSOCIATED WITH EXOPH THALMUS

32 patients (19 female. 13 male)• suffering from Graves' disease with exophthalmus and five without exophthalmus were studied for various autoantibodies including anti-thyroglobulin (ATAB). anti-microsomal antibody (AMAB). anti-parietal antibodies (APAB) and also circulating immune complex (CrC). 43 normal subjects were tested concurrently. Immunofluorescent technique was employed for auto...

متن کامل

Rare association of schizophrenia and unilateral Graves’ disease with contralateral thyroid hemiagenesis in two cases of McCune-Albright syndrome

The classical triad of McCune-Albright syndrome (MAS) consists of polyostotic fibrous dysplasia (FD), skin hyperpigmentation (café-au-lait spots), and endocrine dysfunction, frequently seen in females as precocious puberty. Etiology is genetically based and is explained by mosaicism of activating somatic mutations of the alpha-subunit of Gs protein. Clinical presentation is varied and is depend...

متن کامل

Anticardiolipin Antibodies and Immunoglobulin M and A in Graves’ Disease

Background: Graves’ disease is an autoimmune disease, characterized by the presence of antibodies directed to TSH receptor or nearby regions as well as antibodies to double strands DNA (dsDNA) anticardiolipin and nuclear antibodies. This study evaluated anticardiolipin and rheumatoid factor, such as IgA and IgM antibodies in patients with Graves’ disease. Patients and methods: Anticardiolipin a...

متن کامل

KIR Gene Content Does Not Contribute to Susceptibility to Graves’ Disease

Background: Killer cell immunoglobulin-like receptors (KIR) are expressed on NK cells and a subset of T cells. The variable KIR receptors along with their ligands, HLA class I, influence risk for autoimmune and malignant diseases. Objective: To investigate the KIR gene profiles in relation to susceptibility to Graves’ disease in patients with ophthalmopathy. Methods: KIR genes profiles were ana...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Postgraduate medical journal

دوره 40  شماره 

صفحات  -

تاریخ انتشار 1964